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Structure of the Staphylococcus aureus AgrA LytTR Domain Bound to DNA Reveals a Beta Fold with a Novel Mode of Binding

The LytTR domain is a DNA-binding motif found within the AlgR/AgrA/LytR family of transcription factors that regulate virulence factor and toxin gene expression in pathogenic bacteria. This previously uncharacterized domain lacks sequence similarity with proteins of known structure. The crystal stru...

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Autori principali: Sidote, David J., Barbieri, Christopher M., Wu, Ti, Stock, Ann M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430735/
https://ncbi.nlm.nih.gov/pubmed/18462677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2008.02.011
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