Prediction of enzyme function by combining sequence similarity and protein interactions

BACKGROUND: A number of studies have used protein interaction data alone for protein function prediction. Here, we introduce a computational approach for annotation of enzymes, based on the observation that similar protein sequences are more likely to perform the same function if they share similar...

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Hlavní autoři: Espadaler, Jordi, Eswar, Narayanan, Querol, Enrique, Avilés, Francesc X, Sali, Andrej, Marti-Renom, Marc A, Oliva, Baldomero
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2008
Témata:
Methodology Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430716/
https://ncbi.nlm.nih.gov/pubmed/18505562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-249
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