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Detecting remotely related proteins by their interactions and sequence similarity
The function of an uncharacterized protein is usually inferred either from its homology to, or its interactions with, characterized proteins. Here, we use both sequence similarity and protein interactions to identify relationships between remotely related protein sequences. We rely on the fact that...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1129109/ https://ncbi.nlm.nih.gov/pubmed/15883372 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500831102 |
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