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Detecting remotely related proteins by their interactions and sequence similarity

The function of an uncharacterized protein is usually inferred either from its homology to, or its interactions with, characterized proteins. Here, we use both sequence similarity and protein interactions to identify relationships between remotely related protein sequences. We rely on the fact that...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Espadaler, Jordi, Aragüés, Ramón, Eswar, Narayanan, Marti-Renom, Marc A., Querol, Enrique, Avilés, Francesc X., Sali, Andrej, Oliva, Baldomero
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: National Academy of Sciences 2005
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1129109/
https://ncbi.nlm.nih.gov/pubmed/15883372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500831102
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