Molecular mechanism of use-dependent calcium channel block by phenylalkylamines: Role of inactivation

The role of channel inactivation in the molecular mechanism of calcium (Ca(2+)) channel block by phenylalkylamines (PAA) was analyzed by designing mutant Ca(2+) channels that carry the high affinity determinants of the PAA receptor site [Hockerman, G. H., Johnson, B. D., Scheuer, T., and Catterall,...

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Bibliographic Details
Main Authors: Hering, Steffen, Aczél, Stefan, Kraus, Richard L., Berjukow, Stanislav, Striessnig, Jörg, Timin, Eugen N.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences of the USA 1997
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC24307/
https://ncbi.nlm.nih.gov/pubmed/9371844
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