PREMELANOSOME AMYLOID-LIKE FIBRILS ARE COMPOSED OF ONLY GOLGI-PROCESSED FORMS OF PMEL17 THAT HAVE BEEN PROTEOLYTICALLY PROCESSED IN ENDOSOMES

Melanin pigments are synthesized within specialized organelles called melanosomes and polymerize on intralumenal fibrils that form within melanosome precursors. The fibrils consist of proteolytic fragments derived from Pmel17, a pigment cell-specific integral membrane protein. The intracellular path...

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Bibliographische Detailangaben
Hauptverfasser: Harper, Dawn C., Theos, Alexander C., Herman, Kathryn E., Tenza, Danièle, Raposo, Graça, Marks, Michael S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430631/
https://ncbi.nlm.nih.gov/pubmed/17991747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M708007200
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