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Mechanisms of resistance to ErbB-targeted cancer therapeutics
The ErbB receptors, such as EGFR, have been intensely pursued as targets for cancer therapeutics. However, a large percentage of patients who are initially responsive to ErbB-targeted therapies experience tumor recurrence and become refractory to therapy. In this issue of the JCI, Guix et al. demons...
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Clinical Investigation
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2430503/ https://ncbi.nlm.nih.gov/pubmed/18568082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI36260 |
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