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Mechanisms of resistance to ErbB-targeted cancer therapeutics

The ErbB receptors, such as EGFR, have been intensely pursued as targets for cancer therapeutics. However, a large percentage of patients who are initially responsive to ErbB-targeted therapies experience tumor recurrence and become refractory to therapy. In this issue of the JCI, Guix et al. demons...

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Detaylı Bibliyografya
Asıl Yazarlar: Wang, Qiang, Greene, Mark I.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2008
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430503/
https://ncbi.nlm.nih.gov/pubmed/18568082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI36260
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