Measles virus blind to its epithelial cell receptor remains virulent in rhesus monkeys but cannot cross the airway epithelium and is not shed

The current model of measles virus (MV) pathogenesis implies that apical infection of airway epithelial cells precedes systemic spread. An alternative model suggests that primarily infected lymphatic cells carry MV to the basolateral surface of epithelial cells, supporting MV shedding into the airwa...

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Autores principales: Leonard, Vincent H.J., Sinn, Patrick L., Hodge, Gregory, Miest, Tanner, Devaux, Patricia, Oezguen, Numan, Braun, Werner, McCray, Paul B., McChesney, Michael B., Cattaneo, Roberto
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2008
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430500/
https://ncbi.nlm.nih.gov/pubmed/18568079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI35454
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