Measles virus blind to its epithelial cell receptor remains virulent in rhesus monkeys but cannot cross the airway epithelium and is not shed

The current model of measles virus (MV) pathogenesis implies that apical infection of airway epithelial cells precedes systemic spread. An alternative model suggests that primarily infected lymphatic cells carry MV to the basolateral surface of epithelial cells, supporting MV shedding into the airwa...

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Bibliographic Details
Main Authors: Leonard, Vincent H.J., Sinn, Patrick L., Hodge, Gregory, Miest, Tanner, Devaux, Patricia, Oezguen, Numan, Braun, Werner, McCray, Paul B., McChesney, Michael B., Cattaneo, Roberto
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2008
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430500/
https://ncbi.nlm.nih.gov/pubmed/18568079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI35454
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