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Role of the carboxyl terminal di-leucine in phosphorylation and internalization of C5a receptor

The carboxyl tail of G protein-coupled receptors contains motifs that regulate receptor interactions with intracellular partners. Activation of the human neutrophil complement fragment C5a receptor (C5aR) is terminated by phosphorylation of the carboxyl tail followed by receptor internalization. In...

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Detalhes bibliográficos
Main Authors: Suvorova, Elena S., Gripentrog, Jeannie M., Oppermann, Martin, Miettinen, Heini M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430410/
https://ncbi.nlm.nih.gov/pubmed/18346468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2008.02.004
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