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Label-free and dynamic detection of biomolecular interactions for high-throughput microarray applications

Direct monitoring of primary molecular-binding interactions without the need for secondary reactants would markedly simplify and expand applications of high-throughput label-free detection methods. A simple interferometric technique is presented that monitors the optical phase difference resulting f...

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Autors principals: Özkumur, Emre, Needham, James W., Bergstein, David A., Gonzalez, Rodrigo, Cabodi, Mario, Gershoni, Jonathan M., Goldberg, Bennett B., Ünlü, M. Selim
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430348/
https://ncbi.nlm.nih.gov/pubmed/18523019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711421105
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