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Antagonist affinity measurements at the Gi-coupled human histamine H3 receptor expressed in CHO cells

BACKGROUND: The H3 histamine receptor is a Gi-coupled GPCR that has been proven to exist in different agonist-induced states, including that defined by the protean agonist proxyfan. Several GPCRs are now known to exist in different states. For some of these, antagonist affinity measurement remain co...

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Autore principale: Baker, Jillian G
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430196/
https://ncbi.nlm.nih.gov/pubmed/18538007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2210-8-9
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