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Quercetin augments TRAIL-induced apoptotic death: involvement of the ERK signal transduction pathway

Combined treatment with quercetin and TRAIL induced cytotoxicity and enhanced annexin V staining and poly (ADP-ribose) polymerase (PARP) cleavage in human prostate cancer cell lines DU-145 and PC-3. These indicators of apoptosis resulted from the activation of caspase-8, -9, and -3. Although the exp...

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Detalhes bibliográficos
Main Authors: Kim, Young-Ho, Lee, Dae-Hee, Jeong, Jae-Hoon, Guo, Zong Sheng, Lee, Yong J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430102/
https://ncbi.nlm.nih.gov/pubmed/18377872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2008.02.016
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