The serine protease TMPRSS6 is required to sense iron deficiency

Hepcidin, a liver-derived protein that restricts enteric iron absorption, is the key regulator of body iron content. Several proteins induce expression of the hepcidin-encoding gene Hamp in response to infection or high levels of iron. However, mechanism(s) of Hamp suppression during iron depletion...

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Detaylı Bibliyografya
Asıl Yazarlar: Du, Xin, She, Ellen, Gelbart, Terri, Truksa, Jaroslav, Lee, Pauline, Xia, Yu, Khovananth, Kevin, Mudd, Suzanne, Mann, Navjiwan, Moresco, Eva Marie Y., Beutler, Ernest, Beutler, Bruce
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430097/
https://ncbi.nlm.nih.gov/pubmed/18451267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1157121
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