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The serine protease TMPRSS6 is required to sense iron deficiency
Hepcidin, a liver-derived protein that restricts enteric iron absorption, is the key regulator of body iron content. Several proteins induce expression of the hepcidin-encoding gene Hamp in response to infection or high levels of iron. However, mechanism(s) of Hamp suppression during iron depletion...
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| Hlavní autoři: | , , , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2430097/ https://ncbi.nlm.nih.gov/pubmed/18451267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1157121 |
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