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Increased adiposity on normal diet, but decreased susceptibility to diet-induced obesity in μ-opioid receptor-deficient mice

The mu-opioid receptor encoded by the Oprm1 gene plays a crucial role in the mediation of food reward and drug-induced positive reinforcement, but its genetic deletion has been shown to provide food intake-independent, partial protection from diet-induced obesity. We hypothesized that mu-opioid rece...

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Bibliographic Details
Main Authors: Zuberi, Aamir R., Townsend, Leigh, Patterson, Laurel, Zheng, Huiyuan, Berthoud, Hans-Rudi
Format: Artigo
Language:Inglês
Published: 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2430069/
https://ncbi.nlm.nih.gov/pubmed/18396272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2008.01.047
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