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Decoding of Superimposed Traces Produced by Direct Sequencing of Heterozygous Indels
Direct Sanger sequencing of a diploid template containing a heterozygous insertion or deletion results in a difficult-to-interpret mixed trace formed by two allelic traces superimposed onto each other. Existing computational methods for deconvolution of such traces require knowledge of a reference s...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2429969/ https://ncbi.nlm.nih.gov/pubmed/18654614 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000113 |
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