Heterosubtypic Protection against Pathogenic Human and Avian Influenza Viruses via In Vivo Electroporation of Synthetic Consensus DNA Antigens

BACKGROUND: The persistent evolution of highly pathogenic avian influenza (HPAI) highlights the need for novel vaccination techniques that can quickly and effectively respond to emerging viral threats. We evaluated the use of optimized consensus influenza antigens to provide broad protection against...

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Autors principals: Laddy, Dominick J., Yan, Jian, Kutzler, Michele, Kobasa, Darwyn, Kobinger, Gary P., Khan, Amir S., Greenhouse, Jack, Sardesai, Niranjan Y., Draghia-Akli, Ruxandra, Weiner, David B.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2008
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2429965/
https://ncbi.nlm.nih.gov/pubmed/18575608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002517
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