Epigenetic changes within the promoter region of the HLA-G gene in ovarian tumors

BACKGROUND: Previous findings have suggested that epigenetic-mediated HLA-G expression in tumor cells may be associated with resistance to host immunosurveillance. To explore the potential role of DNA methylation on HLA-G expression in ovarian cancer, we correlated differences in HLA-G expression wi...

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Main Authors: Menendez, Laura, Walker, L DeEtte, Matyunina, Lilya V, Totten, Kimberly A, Benigno, Benedict B, McDonald, John F
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2008
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2429914/
https://ncbi.nlm.nih.gov/pubmed/18498645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-7-43
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