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Preferential activation of the p46 isoform of JNK/SAPK in mouse macrophages by TNFα

A pleiotropic cytokine, tumor necrosis factor-α (TNFα), regulates the expression of multiple macrophage gene products and thus contributes a key role in host defense. In this study, we have investigated the specificity and mechanism of activation of members of the c-Jun-NH(2)-terminal kinase/stress-...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Chan, Edward D., Winston, Brent W., Jarpe, Matthew B., Wynes, Murry W., Riches, David W. H.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1997
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24281/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9371818/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.24.13169
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