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Preferential activation of the p46 isoform of JNK/SAPK in mouse macrophages by TNFα

A pleiotropic cytokine, tumor necrosis factor-α (TNFα), regulates the expression of multiple macrophage gene products and thus contributes a key role in host defense. In this study, we have investigated the specificity and mechanism of activation of members of the c-Jun-NH(2)-terminal kinase/stress-...

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Auteurs principaux: Chan, Edward D., Winston, Brent W., Jarpe, Matthew B., Wynes, Murry W., Riches, David W. H.
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences of the USA 1997
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC24281/
https://ncbi.nlm.nih.gov/pubmed/9371818
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