Signaling and Cross-talk by C5a and UDP in Macrophages Selectively Use PLCβ3 to Regulate Intracellular Free Calcium

Studies in fibroblasts, neurons, and platelets have demonstrated the integration of signals from different G protein-coupled receptors (GPCRs) in raising intracellular free Ca(2+). To study signal integration in macrophages, we screened RAW264.7 cells and bone marrow-derived macrophages (BMDM) for t...

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Détails bibliographiques
Auteurs principaux: Roach, Tamara I. A., Rebres, Robert A., Fraser, Iain D. C., DeCamp, Dianne L., Lin, Keng-Mean, Sternweis, Paul C., Simon, Mel I., Seaman, William E.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2008
Sujets:
Mechanisms of Signal Transduction
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2427365/
https://ncbi.nlm.nih.gov/pubmed/18411281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M800907200
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