Visualization of Polarized Membrane Type 1 Matrix Metalloproteinase Activity in Live Cells by Fluorescence Resonance Energy Transfer Imaging

Membrane type 1 matrix metalloproteinase (MT1-MMP) plays a critical role in cancer cell biology by proteolytically remodeling the extracellular matrix. Utilizing fluorescence resonance energy transfer (FRET) imaging, we have developed a novel biosensor, with its sensing element anchoring at the extr...

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Autors principals: Ouyang, Mingxing, Lu, Shaoying, Li, Xiao-Yan, Xu, Jing, Seong, Jihye, Giepmans, Ben N. G., Shyy, John Y.-J., Weiss, Stephen J., Wang, Yingxiao
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2008
Matèries:
Molecular Basis of Cell and Developmental Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2427332/
https://ncbi.nlm.nih.gov/pubmed/18441011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M709872200
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