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Accommodating Linkage Disequilibrium in Genetic-Association Analyses via Ridge Regression
Large-scale genetic-association studies that take advantage of an extremely dense set of genetic markers have begun to produce very compelling statistical associations between multiple makers exhibiting strong linkage disequilibrium (LD) in a single genomic region and a phenotype of interest. Howeve...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society of Human Genetics
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2427310/ https://ncbi.nlm.nih.gov/pubmed/18252218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2007.10.012 |
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