On the Replication of Genetic Associations: Timing Can Be Everything!

The failure of researchers to replicate genetic-association findings is most commonly attributed to insufficient statistical power, population stratification, or various forms of between-study heterogeneity or environmental influences.(1) Here, we illustrate another potential cause for nonreplicatio...

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Main Authors: Lasky-Su, Jessica, Lyon, Helen N., Emilsson, Valur, Heid, Iris M., Molony, Cliona, Raby, Benjamin A., Lazarus, Ross, Klanderman, Barbara, Soto-Quiros, Manuel E., Avila, Lydiana, Silverman, Edwin K., Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Kronenberg, Florian, Vollmert, Caren, Illig, Thomas, Fox, Caroline S., Levy, Daniel, Laird, Nan, Ding, Xiao, McQueen, Matt B., Butler, Johannah, Ardlie, Kristin, Papoutsakis, Constantina, Dedoussis, George, O'Donnell, Christopher J., Wichmann, H.-Erich, Celedón, Juan C., Schadt, Eric, Hirschhorn, Joel, Weiss, Scott T., Stefansson, Kari, Lange, Christoph
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Human Genetics 2008
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2427263/
https://ncbi.nlm.nih.gov/pubmed/18387595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2008.01.018
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