On the Replication of Genetic Associations: Timing Can Be Everything!

The failure of researchers to replicate genetic-association findings is most commonly attributed to insufficient statistical power, population stratification, or various forms of between-study heterogeneity or environmental influences.(1) Here, we illustrate another potential cause for nonreplicatio...

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Detalhes bibliográficos
Main Authors: Lasky-Su, Jessica, Lyon, Helen N., Emilsson, Valur, Heid, Iris M., Molony, Cliona, Raby, Benjamin A., Lazarus, Ross, Klanderman, Barbara, Soto-Quiros, Manuel E., Avila, Lydiana, Silverman, Edwin K., Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Kronenberg, Florian, Vollmert, Caren, Illig, Thomas, Fox, Caroline S., Levy, Daniel, Laird, Nan, Ding, Xiao, McQueen, Matt B., Butler, Johannah, Ardlie, Kristin, Papoutsakis, Constantina, Dedoussis, George, O'Donnell, Christopher J., Wichmann, H.-Erich, Celedón, Juan C., Schadt, Eric, Hirschhorn, Joel, Weiss, Scott T., Stefansson, Kari, Lange, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Human Genetics 2008
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2427263/
https://ncbi.nlm.nih.gov/pubmed/18387595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2008.01.018
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