On the Replication of Genetic Associations: Timing Can Be Everything!

The failure of researchers to replicate genetic-association findings is most commonly attributed to insufficient statistical power, population stratification, or various forms of between-study heterogeneity or environmental influences.(1) Here, we illustrate another potential cause for nonreplicatio...

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Autori principali: Lasky-Su, Jessica, Lyon, Helen N., Emilsson, Valur, Heid, Iris M., Molony, Cliona, Raby, Benjamin A., Lazarus, Ross, Klanderman, Barbara, Soto-Quiros, Manuel E., Avila, Lydiana, Silverman, Edwin K., Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Kronenberg, Florian, Vollmert, Caren, Illig, Thomas, Fox, Caroline S., Levy, Daniel, Laird, Nan, Ding, Xiao, McQueen, Matt B., Butler, Johannah, Ardlie, Kristin, Papoutsakis, Constantina, Dedoussis, George, O'Donnell, Christopher J., Wichmann, H.-Erich, Celedón, Juan C., Schadt, Eric, Hirschhorn, Joel, Weiss, Scott T., Stefansson, Kari, Lange, Christoph
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Human Genetics 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2427263/
https://ncbi.nlm.nih.gov/pubmed/18387595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2008.01.018
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