Association of the Asporin D14 Allele with Lumbar-Disc Degeneration in Asians

Lumbar-disc degeneration (LDD) is a polygenic disease. Susceptibility genes reported so far are mainly extracellular matrix proteins. D14 allele of asporin (ASPN) is associated with osteoarthritis (OA). Candidate-gene association studies showed that the D14 allele is also significantly associated wi...

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Huvudupphovsmän: Song, You-Qiang, Cheung, Kenneth M.C., Ho, Daniel W.H., Poon, Sandy C.S., Chiba, Kazuhiro, Kawaguchi, Yoshiharu, Hirose, Yuichiro, Alini, Mauro, Grad, Sibylle, Yee, Anita F.Y., Leong, John C.Y., Luk, Keith D.K., Yip, Shea-Ping, Karppinen, Jaro, Cheah, Kathryn S.E., Sham, Pak, Ikegawa, Shiro, Chan, Danny
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2008
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Report
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2427233/
https://ncbi.nlm.nih.gov/pubmed/18304494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2007.12.017
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