Association between promoter -1607 polymorphism of MMP1 and Lumbar Disc Disease in Southern Chinese

BACKGROUND: Matrix metalloproteinases (MMPs) are involved in the degradation of the extracellular matrix of the intervertebral disc. A SNP for guanine insertion/deletion (G/D), the -1607 promoter polymorphism, of the MMP1 gene was found significantly affecting promoter activity and corresponding tra...

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Detalhes bibliográficos
Main Authors: Song, You-Qiang, Ho, Daniel WH, Karppinen, Jaro, Kao, Patrick YP, Fan, Bao-Jian, Luk, Keith DK, Yip, Shea-Ping, Leong, John CY, Cheah, Kathryn SE, Sham, Pak, Chan, Danny, Cheung, Kenneth MC
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386444/
https://ncbi.nlm.nih.gov/pubmed/18439317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-9-38
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