EFFICIENT AND DURABLE GENE TRANSFER TO THE TRANSPLANTED HEART USING ADENO-ASSOCIATED VIRUS 9 VECTOR

BACKGROUND: We studied the efficacy and durability of recombinant adeno-associated virus serotype 9 (rAAV9) vector mediated gene transfer to the transplanted rat heart. METHODS: ArAAV9-CMV-lacZ vector diluted in cold (4°C)University of Wisconsin solution was used to perfuse the rat coronary vasculat...

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Detalhes bibliográficos
Main Authors: Miyagi, Naoto, Rao, Vinay P, Ricci, Davide, Du, Zeji, Byrne, Guerard W, Bailey, Kent R, Nakai, Hiroyuki, Russell, Stephen J, McGregor, Christopher GA
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2426957/
https://ncbi.nlm.nih.gov/pubmed/18442723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.healun.2008.01.025
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