Patients with rheumatoid arthritis have an altered circulatory aggrecan profile

BACKGROUND: Rheumatoid arthritis (RA) is a chronic auto-immune disease with extensive articular cartilage destruction. Aggrecan depletion, mediated by aggrecanases is one of the first signs of early cartilage erosion. We investigated, whether measurement of aggrecan and fragments thereof in serum, c...

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Detalhes bibliográficos
Main Authors: Rousseau, Jean C, Sumer, Eren U, Hein, Gert, Sondergaard, Bodil C, Madsen, Suzi H, Pedersen, Christian, Neumann, Thomas, Mueller, Andreas, Qvist, Per, Delmas, Pierre, Karsdal, Morten A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2426686/
https://ncbi.nlm.nih.gov/pubmed/18507823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2474-9-74
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