Patients with rheumatoid arthritis have an altered circulatory aggrecan profile

BACKGROUND: Rheumatoid arthritis (RA) is a chronic auto-immune disease with extensive articular cartilage destruction. Aggrecan depletion, mediated by aggrecanases is one of the first signs of early cartilage erosion. We investigated, whether measurement of aggrecan and fragments thereof in serum, c...

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Bibliografiske detaljer
Main Authors: Rousseau, Jean C, Sumer, Eren U, Hein, Gert, Sondergaard, Bodil C, Madsen, Suzi H, Pedersen, Christian, Neumann, Thomas, Mueller, Andreas, Qvist, Per, Delmas, Pierre, Karsdal, Morten A
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2008
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2426686/
https://ncbi.nlm.nih.gov/pubmed/18507823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2474-9-74
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