Patients with rheumatoid arthritis have an altered circulatory aggrecan profile

BACKGROUND: Rheumatoid arthritis (RA) is a chronic auto-immune disease with extensive articular cartilage destruction. Aggrecan depletion, mediated by aggrecanases is one of the first signs of early cartilage erosion. We investigated, whether measurement of aggrecan and fragments thereof in serum, c...

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Autors principals: Rousseau, Jean C, Sumer, Eren U, Hein, Gert, Sondergaard, Bodil C, Madsen, Suzi H, Pedersen, Christian, Neumann, Thomas, Mueller, Andreas, Qvist, Per, Delmas, Pierre, Karsdal, Morten A
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2008
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2426686/
https://ncbi.nlm.nih.gov/pubmed/18507823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2474-9-74
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