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Pdx-1 and Ptf1a concurrently determine fate specification of pancreatic multipotent progenitor cells
The pancreas is derived from a pool of multipotent progenitor cells (MPCs) that co-express Pdx-1 and Ptf1a. To more precisely define how the individual and combined loss of Pdx-1 and Ptf1a affects pancreatic MPC specification and differentiation we derived and studied mice bearing a novel Ptf1a(YFP)...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2425677/ https://ncbi.nlm.nih.gov/pubmed/18294628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2008.01.011 |
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