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Pdx-1 and Ptf1a concurrently determine fate specification of pancreatic multipotent progenitor cells

The pancreas is derived from a pool of multipotent progenitor cells (MPCs) that co-express Pdx-1 and Ptf1a. To more precisely define how the individual and combined loss of Pdx-1 and Ptf1a affects pancreatic MPC specification and differentiation we derived and studied mice bearing a novel Ptf1a(YFP)...

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Autors principals: Burlison, Jared S., Long, Qiaoming, Fujitani, Yoshio, Wright, Christopher V.E., Magnuson, Mark A.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2425677/
https://ncbi.nlm.nih.gov/pubmed/18294628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2008.01.011
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