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Correlation between simulated physicochemical properties and hemolycity of protegrin-like antimicrobial peptides: Predicting experimental toxicity

The therapeutic, antibiotic potential of antimicrobial peptides can be prohibitively diminished because of the cytotoxicity and hemolytic profiles they exhibit. Quantifying and predicting antimicrobial peptide toxicity against host cells is thus an important goal of AMP related research. In this wor...

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Detalhes bibliográficos
Principais autores: Langham, Allison A., Khandelia, Himanshu, Schuster, Benjamin, Waring, Alan J., Lehrer, Robert I., Kaznessis, Yiannis N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2424260/
https://ncbi.nlm.nih.gov/pubmed/18455267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2008.03.018
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