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Dusp6(Mkp3) is a negative feedback regulator of FGF stimulated ERK signaling during mouse development

Mitogen-activated protein kinase (MAPK) pathways are major mediators of extracellular signals that are transduced to the nucleus. MAPK signaling is attenuated at several levels and one class of dual-specificity phosphatases, the MAPK phosphatases (MKPs), inhibit MAPK signaling by dephosphorylating a...

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Detalhes bibliográficos
Main Authors: Li, Chaoying, Scott, Daryl A., Hatch, Ekaterina, Tian, Xiaoyan, Mansour, Suzanne L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2424197/
https://ncbi.nlm.nih.gov/pubmed/17164422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.02701
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