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Phagocytosis of rod outer segments by retinal pigment epithelial cells requires αvβ5 integrin for binding but not for internalization

Phagocytosis of shed photoreceptor rod outer segments (ROS) by the retinal pigment epithelium (RPE) is essential for retinal function. Here, we demonstrate that this process requires αvβ5 integrin, rather than αvβ3 integrin utilized by systemic macrophages. Although adult rat RPE expressed both αvβ3...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Finnemann, Silvia C., Bonilha, Vera L., Marmorstein, Alan D., Rodriguez-Boulan, Enrique
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 1997
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC24241/
https://ncbi.nlm.nih.gov/pubmed/9371778
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