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Mapping gene expression quantitative trait loci by singular value decomposition and independent component analysis

BACKGROUND: The combination of gene expression profiling with linkage analysis has become a powerful paradigm for mapping gene expression quantitative trait loci (eQTL). To date, most studies have searched for eQTL by analyzing gene expression traits one at a time. As thousands of expression traits...

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Main Authors: Biswas, Shameek, Storey, John D, Akey, Joshua M
格式: Artigo
語言:Inglês
出版: BioMed Central 2008
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2424053/
https://ncbi.nlm.nih.gov/pubmed/18492285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-244
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