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Choline deficiency in mice and humans is associated with increased plasma homocysteine concentration after a methionine load

BACKGROUND: Elevated concentrations of homocysteine in blood may be an independent risk factor for the development of atherosclerosis. Elevated homocysteine concentrations can be caused by decreased methylation of homocysteine to form methionine, as occurs in folate deficiency. A parallel pathway ex...

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Bibliographic Details
Main Authors: Costa, Kerry-Ann da, Gaffney, Christopher E, Fischer, Leslie M, Zeisel, Steven H
Format: Artigo
Language:Inglês
Published: 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2424020/
https://ncbi.nlm.nih.gov/pubmed/15699233
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