Hypocretin/orexin and nociceptin/orphanin FQ coordinately regulate analgesia in a mouse model of stress-induced analgesia

Stress-induced analgesia (SIA) is a key component of the defensive behavioral “fight-or-flight” response. Although the neural substrates of SIA are incompletely understood, previous studies have implicated the hypocretin/orexin (Hcrt) and nociceptin/orphanin FQ (N/OFQ) peptidergic systems in the reg...

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Autors principals: Xie, Xinmin, Wisor, Jonathan P., Hara, Junko, Crowder, Tara L., LeWinter, Robin, Khroyan, Taline V., Yamanaka, Akihiro, Diano, Sabrina, Horvath, Tamas L., Sakurai, Takeshi, Toll, Lawrence, Kilduff, Thomas S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2008
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423866/
https://ncbi.nlm.nih.gov/pubmed/18551194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI35115
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