Absence of Chx10 Causes Neural Progenitors to Persist in the Adult Retina

PURPOSE: Mutation of the Chx10 homeobox gene in mice and humans causes congenital blindness and microphthalmia (small eyes). This study used Chx10(−/−) (ocular retardation) mice to investigate how lack of Chx10 affects progenitor/stem cell behavior in the retina and ciliary epithelium (CE). METHODS:...

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Main Authors: Dhomen, Nathalie S., Balaggan, Kam S., Pearson, Rachael A., Bainbridge, James W., Levine, Edward M., Ali, Robin R., Sowden, Jane C.
格式: Artigo
語言:Inglês
出版: 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423807/
https://ncbi.nlm.nih.gov/pubmed/16384989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.05-0428
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