Mammalian capping enzyme complements mutant Saccharomyces cerevisiae lacking mRNA guanylyltransferase and selectively binds the elongating form of RNA polymerase II

5′-Capping is an early mRNA modification that has important consequences for downstream events in gene expression. We have isolated mammalian cDNAs encoding capping enzyme. They contain the sequence motifs characteristic of the nucleotidyl transferase superfamily. The predicted mouse and human enzym...

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Bibliographische Detailangaben
Hauptverfasser: Yue, Zhenyu, Maldonado, Edio, Pillutla, Renuka, Cho, Helen, Reinberg, Danny, Shatkin, Aaron J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences of the USA 1997
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC24235/
https://ncbi.nlm.nih.gov/pubmed/9371772
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