Lysophosphatidic Acid Protects Cancer Cells from Histone Deacetylase (HDAC) Inhibitor-induced Apoptosis through Activation of HDAC

Histone deacetylases (HDACs) catalyze the removal of acetyl groups from histones and contribute to transcriptional repression. In addition, the HDAC inhibitors induce apoptosis in cancer cells through alterations in histone acetylation and activation of the tumor necrosis factor-related apoptosis-in...

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Hlavní autoři: Ishdorj, Ganchimeg, Graham, Bonnie A., Hu, Xiaojie, Chen, Jing, Johnston, James B., Fang, Xianjun, Gibson, Spencer B.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2008
Témata:
Mechanisms of Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423270/
https://ncbi.nlm.nih.gov/pubmed/18408217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M710177200
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