MURC, a Muscle-Restricted Coiled-Coil Protein That Modulates the Rho/ROCK Pathway, Induces Cardiac Dysfunction and Conduction Disturbance

We identified a novel muscle-restricted putative coiled-coil protein, MURC, which is evolutionarily conserved from frog to human. MURC was localized to the cytoplasm with accumulation in the Z-line of the sarcomere in the murine adult heart. MURC mRNA expression in the heart increased during the dev...

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Autors principals: Ogata, Takehiro, Ueyama, Tomomi, Isodono, Koji, Tagawa, Masashi, Takehara, Naofumi, Kawashima, Tsuneaki, Harada, Koichiro, Takahashi, Tomosaburo, Shioi, Tetsuo, Matsubara, Hiroaki, Oh, Hidemasa
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2008
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423172/
https://ncbi.nlm.nih.gov/pubmed/18332105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02186-07
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