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Bud23 Methylates G1575 of 18S rRNA and Is Required for Efficient Nuclear Export of Pre-40S Subunits

BUD23 was identified from a bioinformatics analysis of Saccharomyces cerevisiae genes involved in ribosome biogenesis. Deletion of BUD23 leads to severely impaired growth, reduced levels of the small (40S) ribosomal subunit, and a block in processing 20S rRNA to 18S rRNA, a late step in 40S maturati...

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Bibliographic Details
Main Authors: White, Joshua, Li, Zhihua, Sardana, Richa, Bujnicki, Janusz M., Marcotte, Edward M., Johnson, Arlen W.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423152/
https://ncbi.nlm.nih.gov/pubmed/18332120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01674-07
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