DEC1 Modulates the Circadian Phase of Clock Gene Expression

DEC1 suppresses CLOCK/BMAL1-enhanced promoter activity, but its role in the circadian system of mammals remains unclear. Here we examined the effect of Dec1 overexpression or deficiency on circadian gene expression triggered with 50% serum. Overexpression of Dec1 delayed the phase of clock genes suc...

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Hlavní autoři: Nakashima, Ayumu, Kawamoto, Takeshi, Honda, Kiyomasa K., Ueshima, Taichi, Noshiro, Mitsuhide, Iwata, Tomoyuki, Fujimoto, Katsumi, Kubo, Hiroshi, Honma, Sato, Yorioka, Noriaki, Kohno, Nobuoki, Kato, Yukio
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423136/
https://ncbi.nlm.nih.gov/pubmed/18411297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02168-07
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