DEC1 Modulates the Circadian Phase of Clock Gene Expression

DEC1 suppresses CLOCK/BMAL1-enhanced promoter activity, but its role in the circadian system of mammals remains unclear. Here we examined the effect of Dec1 overexpression or deficiency on circadian gene expression triggered with 50% serum. Overexpression of Dec1 delayed the phase of clock genes suc...

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Detalhes bibliográficos
Main Authors: Nakashima, Ayumu, Kawamoto, Takeshi, Honda, Kiyomasa K., Ueshima, Taichi, Noshiro, Mitsuhide, Iwata, Tomoyuki, Fujimoto, Katsumi, Kubo, Hiroshi, Honma, Sato, Yorioka, Noriaki, Kohno, Nobuoki, Kato, Yukio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423136/
https://ncbi.nlm.nih.gov/pubmed/18411297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02168-07
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