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Both CD4(+) and CD8(+) T Cells Respond to Antigens Fused to Anthrax Lethal Toxin

The lethal toxin produced by Bacillus anthracis is a bipartite toxin in which the first protein, protective antigen (PA), transports the second protein, lethal factor, across the host cell membrane. We have previously shown that CD8(+) T-cell epitopes fused to a nontoxic derivative of lethal factor...

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Autores principales: Shaw, Christine A., Starnbach, Michael N.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423103/
https://ncbi.nlm.nih.gov/pubmed/18347032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01718-07
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