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Stimulation of CD8(+) T Cells following Diphtheria Toxin-Mediated Antigen Delivery into Dendritic Cells

Recognition and clearance of many intracellular pathogens requires the activation and subsequent effector functions of CD8(+) T lymphocytes. To stimulate CD8(+) T cells by immunization, the target antigens must be delivered into the cytosol of host cells. There they can be processed into peptides an...

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Detalhes bibliográficos
Main Authors: Shaw, Christine A., Starnbach, Michael N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1360329/
https://ncbi.nlm.nih.gov/pubmed/16428746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.74.2.1001-1008.2006
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