Tuberculous Granulomas Are Hypoxic in Guinea Pigs, Rabbits, and Nonhuman Primates

Understanding the physical characteristics of the local microenvironment in which Mycobacterium tuberculosis resides is an important goal that may allow the targeting of metabolic processes to shorten drug regimens. Pimonidazole hydrochloride (Hypoxyprobe) is an imaging agent that is bioreductively...

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Bibliografske podrobnosti
Main Authors: Via, Laura E., Lin, P. Ling, Ray, Sonja M., Carrillo, Jose, Allen, Shannon Sedberry, Eum, Seok Yong, Taylor, Kimberly, Klein, Edwin, Manjunatha, Ujjini, Gonzales, Jacqueline, Lee, Eun Gae, Park, Seung Kyu, Raleigh, James A., Cho, Sang Nae, McMurray, David N., Flynn, JoAnne L., Barry, Clifton E.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2008
Teme:
Bacterial Infections
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423064/
https://ncbi.nlm.nih.gov/pubmed/18347040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01515-07
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