Tuberculous Granulomas Are Hypoxic in Guinea Pigs, Rabbits, and Nonhuman Primates

Understanding the physical characteristics of the local microenvironment in which Mycobacterium tuberculosis resides is an important goal that may allow the targeting of metabolic processes to shorten drug regimens. Pimonidazole hydrochloride (Hypoxyprobe) is an imaging agent that is bioreductively...

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מידע ביבליוגרפי
Main Authors: Via, Laura E., Lin, P. Ling, Ray, Sonja M., Carrillo, Jose, Allen, Shannon Sedberry, Eum, Seok Yong, Taylor, Kimberly, Klein, Edwin, Manjunatha, Ujjini, Gonzales, Jacqueline, Lee, Eun Gae, Park, Seung Kyu, Raleigh, James A., Cho, Sang Nae, McMurray, David N., Flynn, JoAnne L., Barry, Clifton E.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology (ASM) 2008
נושאים:
Bacterial Infections
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423064/
https://ncbi.nlm.nih.gov/pubmed/18347040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01515-07
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