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Nasal Immunization with Lactococcus lactis Expressing the Pneumococcal Protective Protein A Induces Protective Immunity in Mice

Nisin-controlled gene expression was used to develop a recombinant strain of Lactococcus lactis that is able to express the pneumococcal protective protein A (PppA) on its surface. Immunodetection assays confirmed that after the induction with nisin, the PppA antigen was predictably and efficiently...

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Bibliografiset tiedot
Päätekijät: Medina, Marcela, Villena, Julio, Vintiñi, Elisa, Hebert, Elvira María, Raya, Raúl, Alvarez, Susana
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423061/
https://ncbi.nlm.nih.gov/pubmed/18390997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00119-08
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