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Heterogeneity in the Polarity of Nra Regulatory Effects on Streptococcal Pilus Gene Transcription and Virulence

Transcription of several key virulence factors of Streptococcus pyogenes is under the control of Mga and Nra/RofA. In an M serotype 49 (M49) strain, Nra is a negative regulator of pilus gene transcription; also, Nra represses mga expression, leading to downregulation of the M protein surface fibril...

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Detalhes bibliográficos
Main Authors: Luo, Feng, Lizano, Sergio, Bessen, Debra E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423052/
https://ncbi.nlm.nih.gov/pubmed/18347035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01567-07
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