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Heterogeneity in the Polarity of Nra Regulatory Effects on Streptococcal Pilus Gene Transcription and Virulence

Transcription of several key virulence factors of Streptococcus pyogenes is under the control of Mga and Nra/RofA. In an M serotype 49 (M49) strain, Nra is a negative regulator of pilus gene transcription; also, Nra represses mga expression, leading to downregulation of the M protein surface fibril...

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Autors principals: Luo, Feng, Lizano, Sergio, Bessen, Debra E.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423052/
https://ncbi.nlm.nih.gov/pubmed/18347035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01567-07
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