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Array painting reveals a high frequency of balanced translocations in breast cancer cell lines that break in cancer-relevant genes

Chromosome translocations in the common epithelial cancers are abundant, yet little is known about them. They have been thought to be almost all unbalanced and therefore dismissed as mostly mediating tumour suppressor loss. We present a comprehensive analysis by array painting of the chromosome tran...

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Detalhes bibliográficos
Main Authors: Howarth, KD, Blood, KA, Ng, BL, Beavis, JC, Chua, Y, Cooke, SL, Raby, S, Ichimura, K, Collins, VP, Carter, NP, Edwards, PAW
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423006/
https://ncbi.nlm.nih.gov/pubmed/18084325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1210993
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