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A Yeast Genetic Screen Reveals a Critical Role for the Pore Helix Domain in TRP Channel Gating
TRP cation channels function as cellular sensors in uni- and multicellular eukaryotes. Despite intensive study, the mechanisms of TRP channel activation by chemical or physical stimuli remain poorly understood. To identify amino acid residues crucial for TRP channel gating, we developed an unbiased,...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2422846/ https://ncbi.nlm.nih.gov/pubmed/18466747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2008.04.012 |
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